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Studentship - Improved methods to encode molecular activity with shape and polarity
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| Scholarships or student grants level |
Graduate
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Countries where scholarship or student grant is applicable |
United Kingdom /
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Universities where scholarships or student grants are applicable |
University of Manchester /
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Countries which are eligible for the scholarhips or student grants |
Austria / Belgium / Bulgaria / Cyprus / Czech Republic / Denmark / Estonia / Finland / France / Germany / Greece / Hungary / Ireland / Italy / Latvia / Lithuania / Luxembourg / Malta / Netherlands / Poland / Portugal / Romania / Slovakia / Slovenia / Spain / Sweden / United Kingdom /
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| Scholarships or student grants program description |
Funding: Funding available for eligible UK/EU applicants.
Subject Areas
* Biochemistry
* Bioinformatics
* Biomolecular Sciences
* Biotechnology
* Pharmacology
* Structural Biology
Description
Shape and charge are key determinants in describing the relationships between small molecules of pharmaceutical relevance, and are therefore important in drug design and virtual screening processes. The same properties also describe many features of proteins and other biological macromolecules. This may simply be as a complementary surface to a drug-like molecule, but also includes the chemical underpinning of biological processes such as catalysis by enzymes. This collaborative PhD is between the groups of Andrew Grant at the Alderley Park site of AstraZeneca, and Jim Warwicker at the University of Manchester. Both groups are active in developing methods for computing solvation properties, either a tool to aid drug design or as a probe to understand biological processes.
This project will run between the two groups to improve techniques by learning from these related project areas. For example, can the tools used to cluster drug-like molecules also be used to classify macromolecules? Conversely, could a knowledge of catalysis in terms of shape and charge, aid inhibitor design? Where the therapeutic molecules are themselves macromolecules, antibodies for example, which are the most appropriate methods for modelling interactions with a receptor?
The student will benefit from interactions within a computational chemistry environment at AstraZeneca that is directed ultimately towards pharmaceutical discovery, and from a background grouping at Manchester with bioinformatics and systems biology components. This PhD is computational, with substantial resource (e.g. computer clusters, databases) at both sites.
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Study fields funded by the scholarships or student grants |
Computing, Maths And It / Sciences: Pure And Applied /
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| Official scholarships or student grants website: |
click here to go to the official website
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| Official scholarship or student grants email: |
j.warwicker@manchester.ac.uk
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Borse di studi
Junior Fulbright Program
United States
Ford Foundation International Fellows Program
Worldwide
Rotary Fellowships
Global Network of Community Volunteers
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| Student grants |
IDD Postgraduate Taught Masters Bursaries
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THE ANGLO-DANISH SCHOLARSHIPS
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LLM Maritime and Marine Law /Maritime and Marine Law and Practice
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The Journal of Sound and Vibration P.E. Doak Award
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Wesley Full Tuition Grant Program
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CarDonors.com Scholarship
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PAUL H. LAUER, JR. SCHOLARSHIP
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Terry Steele Jazz Scholarship
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AMBUCS Health Professions Award
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Mary Weaver Evans Scholarship
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PHN Charitable Foundation Nursing Scholarship
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| Universita |
Hofstra University, United States - New York, Hempstead
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South Florida Community College, United States- Florida, Avon Park
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Judson College, United States- Alabama, Marion
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Lincoln University, United Kingdom, Lincoln
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California Culinary Academy, United States- California, San Francisco
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Occidental College, United States- California, Los Angeles
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Groupe Ecole supérieure de Commerce de Dijon-Bourgogne, France, Dijon
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Liechtenstein University of Applied Sciences, Liechtenstein, Vaduz
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Somerset Community College, United States- Kentucky, Somerset
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Saint Martin's University, United States- Washington, Lacey
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